Helmet CPAP to treat hypoxic pneumonia outside the ICU: an observational study during the COVID-19 outbreak
نویسندگان
چکیده
Abstract Background Respiratory failure due to COVID-19 pneumonia is associated with high mortality and may overwhelm health care systems, the surge of patients requiring advanced respiratory support. Shortage intensive unit (ICU) beds required many be treated outside ICU despite severe gas exchange impairment. Helmet an effective interface provide continuous positive airway pressure (CPAP) noninvasively. We report data about usefulness helmet CPAP during pandemic, either as treatment, a bridge intubation or rescue therapy for limitations (DNI). Methods In this observational study we collected regarding failing standard oxygen (i.e., non-rebreathing mask) free flow system. Patients’ were recorded before, at initiation treatment once day, thereafter. was defined composite outcome death. Results A total 306 included; 42% deemed DNI. successful in 69% full 28% DNI ( P < 0.001). With CPAP, PaO 2 /FiO ratio doubled from 100 200 mmHg 0.001); rate decreased 28 [22–32] 24 [20–29] breaths per minute, C-reactive protein, time mask failure, age, number comorbidities independently failure. maintained 6 [3–9] days, almost continuously first two days. None died before wards. Conclusions feasible several days ICU, persistent impairment exchange. It used, without escalating intubation, majority after failed. could benefit improve survival. Trial Registration : NCT04424992
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ژورنال
عنوان ژورنال: Critical Care
سال: 2021
ISSN: ['1364-8535', '1466-609X']
DOI: https://doi.org/10.1186/s13054-021-03502-y